Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.36 |
| ▸ | AHR | P35869 | 5/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2078453 | 0.81 | AHR (0.35) | TDP2AHRCMA1PDK2EIF2AK2 | |
| SCHEMBL1163094 | 0.77 | GRIA1 (0.41) | TDP2AHRCMA1PDK2CA9 | |
| SCHEMBL1163301 | 0.74 | AHR (0.53) | TDP2AHRCMA1PDK2 | |
| SCHEMBL12157511 | 0.74 | GRIA1 (0.41) | TDP2AHRCMA1PDK2CA9 | |
| SCHEMBL13037464 | 0.73 | CA9 (0.37) | TDP2AHRDRD2DRD1DRD4 | |
| SCHEMBL5501177 | 0.72 | AHR (0.56) | TDP2AHRDRD2DRD1DRD4 | |
| SCHEMBL27136456 | 0.70 | CA9 (0.44) | CA9 | |
| SCHEMBL10713979 | 0.68 | TDP2 (0.49) | TDP2AHRPDK2 | |
| SCHEMBL19615469 | 0.68 | AHR (0.39) | TDP2AHRDRD2DRD1DRD4 | |
| SCHEMBL151642 | 0.67 | HDAC3 (0.40) | TDP2AHRCMA1PDK2EIF2AK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |