Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301531 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL8319598 | 0.86 | APLNR (0.94) | APLNRCYP2C19SLC6A4CYP1A2ALOX15 | |
| SCHEMBL5883941 | 0.86 | APLNR (0.67) | APLNRCYP2C19SLC6A4CYP1A2ALOX15 | |
| SCHEMBL849927 | 0.79 | APLNR (0.80) | APLNRCYP2C19SLC6A4CYP1A2ALOX15 | |
| SCHEMBL11285851 | 0.76 | — | — | |
| SCHEMBL23590185 | 0.75 | APLNR (0.65) | APLNRCYP2C19SLC6A4CYP1A2ALOX15 | |
| SCHEMBL17212627 | 0.75 | APLNR (0.65) | APLNRCYP2C19SLC6A4CYP1A2ALOX15 | |
| SCHEMBL8318891 | 0.75 | APLNR (0.65) | APLNRCYP2C19SLC6A4CYP1A2ALOX15 | |
| SCHEMBL16665157 | 0.74 | CYP2C19 (0.48) | APLNRCYP2C19SLC6A4CYP1A2ALOX15 | |
| SCHEMBL2670798 | 0.74 | CYP2C19 (0.48) | APLNRCYP2C19SLC6A4CYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276484-B2 | Dipeptide inhibitors of β-secretase | ELAN PHARMACEUTICALS, INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050182138-A1 | Dipeptide inhibitors of beta-secretase | ELAN PHARMACEUTICALS, INC. | 2005-08-18 | — | — | US | disclosed |
| US-6864240-B1 | Dipeptide inhibitors of β-secretase | ELAN PHARMACEUTICALS, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| EP-0240212-B1 | PREPARATION OF HIGHLY PURE ALPHA-METHYLSTYRENE POLYMER | THE DOW CHEMICAL COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4748222-A | Preparation of highly pure alpha-methylstyrene polymer | THE DOW CHEMICAL COMPANY (US) | 1988-05-31 | — | — | US | disclosed |
| EP-0240212-A2 | Preparation of highly pure alpha-methylstyrene polymer | THE DOW CHEMICAL COMPANY (US) | 1987-10-07 | — | — | EP | disclosed |
| EP-0058217-B1 | A PROCESS FOR PRODUCING A RANDOM COPOLYMER AND RANDOM COPOLYMER | PHILLIPS PETROLEUM COMPANY (US) | 1987-05-06 | — | — | EP | disclosed |
| EP-0058217-A1 | A process for producing a random copolymer and random copolymer | PHILLIPS PETROLEUM COMPANY (US) | 1982-08-25 | — | — | EP | disclosed |
| US-4277591-A | ORGANOLITHIUM INITIATOR AND AN ORGANIC COMPOUND OF SODIUM, POTASSIUM, RUBIDIUM, OR CESIUM | PHILLIPS PETROLEUM COMPANY (US) | 1981-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182138-A1 | Dipeptide inhibitors of beta-secretase | BACE1, APP, BACE2 | APLNR 127/4885CYP2C19 4626/4885SLC6A4 3553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.