Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441180 | 0.84 | — | — | |
| SCHEMBL28374092 | 0.84 | — | — | |
| SCHEMBL140227 | 0.81 | — | — | |
| SCHEMBL20919462 | 0.81 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2 | |
| SCHEMBL1283759 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL3021853 | 0.81 | — | — | |
| SCHEMBL29958227 | 0.81 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2 | |
| Bromide SCHEMBL29963987 | 0.79 | HSD17B10 (0.43) | HSD17B10SMN1; SMN2 | |
| SCHEMBL740177 | 0.78 | — | — | |
| SCHEMBL4060902 | 0.73 | OPRD1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740574-A2 | 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES | Otsuka Pharmaceutical Company, Limited (JP) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105778-A2 | 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-11-10 | — | — | WO | disclosed |