Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.52 |
| ▸ | BTK | Q06187 | 3/20 | 0.44 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506070 | 0.78 | MTNR1B (0.52) | MTNR1AMTNR1BIRAK4MAPK7 | |
| SCHEMBL4778616 | 0.76 | AAK1 (0.40) | BTKCCRL2 | |
| SCHEMBL4778620 | 0.76 | AAK1 (0.40) | BTKCCRL2 | |
| SCHEMBL2334753 | 0.74 | KDM4E (0.49) | BTKPIK3CAMTORPRKDC | |
| SCHEMBL2334756 | 0.74 | KDM4E (0.49) | BTKPIK3CAMTORPRKDC | |
| SCHEMBL3120000 | 0.74 | KDM4E (0.49) | BTKPIK3CAMTORPRKDC | |
| SCHEMBL5514592 | 0.72 | IRAK4 (0.41) | BTKIRAK4 | |
| SCHEMBL5514596 | 0.72 | IRAK4 (0.41) | BTKIRAK4 | |
| SCHEMBL13145838 | 0.72 | DDR2 (0.44) | MTNR1AMTNR1BBTKPIK3CAMTOR | |
| SCHEMBL4879924 | 0.71 | SLC2A1 (0.51) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799676-A2 | NEW BICYCLIC ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006032466-A2 | NEW BICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-30 | — | — | WO | disclosed |