Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 14/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502668 | 1.00 | AKR1C3 (0.46) | AKR1C3KDM4ELMNAFFAR1FFAR4 | |
| SCHEMBL5654914 | 0.89 | KDM4E (0.55) | AKR1C3KDM4ELMNAAKR1C4AKR1C1 | |
| SCHEMBL5654907 | 0.89 | KDM4E (0.55) | AKR1C3KDM4ELMNAAKR1C4AKR1C1 | |
| SCHEMBL4972553 | 0.85 | FFAR1 (0.48) | FFAR1FFAR4LTB4RLTB4R2 | |
| SCHEMBL4969599 | 0.83 | AKR1C3 (0.52) | AKR1C3KDM4ELMNAAKR1C2LTB4R | |
| SCHEMBL4969588 | 0.83 | AKR1C3 (0.52) | AKR1C3KDM4ELMNAAKR1C2LTB4R | |
| SCHEMBL4970102 | 0.81 | FFAR4 (0.49) | LMNAFFAR1FFAR4LTB4RLTB4R2 | |
| SCHEMBL5651537 | 0.80 | ALDH1A1 (0.46) | AKR1C3KDM4EAKR1C2LTB4RLTB4R2 | |
| SCHEMBL5651543 | 0.80 | ALDH1A1 (0.46) | AKR1C3KDM4EAKR1C2LTB4RLTB4R2 | |
| SCHEMBL4970822 | 0.80 | RARB (0.46) | FFAR1FFAR4LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781274-A1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE RECEPTORS OF PPAR TYPE AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2007-05-09 | — | — | EP | claimed |
| WO-2006018325-A1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE RECEPTORS OF PPAR TYPE AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-02-23 | — | — | WO | claimed |