Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PI4KA | P42356 | 1/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180024 | 0.89 | ADORA3 (0.72) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL5511103 | 0.88 | ADORA3 (0.56) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL5508361 | 0.86 | TSHR (0.70) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL5507191 | 0.85 | ADORA3 (0.69) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL12200089 | 0.85 | ADORA3 (0.69) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL15144301 | 0.85 | ADORA3 (0.69) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL7735031 | 0.85 | ADORA3 (0.69) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL5509724 | 0.85 | ADORA3 (0.46) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL6574020 | 0.82 | ADORA3 (0.66) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL4649323 | 0.82 | PI4KA (0.68) | ADORA3ADORA2AADORA2BADORA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537133-B1 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | CV THERAPEUTICS INC (US) | 2007-07-25 | — | — | EP | disclosed |