Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499243 | 0.88 | CTSA (0.36) | HSP90AA1HSP90AB1NPC1ALDH1A1RAB9A | |
| SCHEMBL5505434 | 0.87 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1NPC1ALDH1A1RAB9A | |
| SCHEMBL5505122 | 0.86 | EDNRB (0.34) | NPC1ALDH1A1RAB9ACTSAGRM4 | |
| SCHEMBL5506437 | 0.85 | ITGB1 (0.34) | HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL2286121 | 0.82 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1NPC1ALDH1A1RAB9A | |
| SCHEMBL2286974 | 0.82 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1NPC1ALDH1A1RAB9A | |
| SCHEMBL5502566 | 0.82 | NR4A2 (0.40) | HSP90AA1HSP90AB1ALDH1A1CTSA | |
| SCHEMBL2292233 | 0.81 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1NPC1ALDH1A1RAB9A | |
| SCHEMBL2286995 | 0.81 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1NPC1ALDH1A1RAB9A | |
| SCHEMBL5498610 | 0.81 | CYP1A2 (0.33) | NPC1ALDH1A1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773124-A1 | A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE | Bayer CropScience Aktiengesellschaft (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006008159-A1 | A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE | BAYER CROPSCIENCE AG (DE) | 2006-01-26 | — | — | WO | disclosed |