Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2291626 | 0.92 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1ALDH1A1KCNJ5KCNJ3 | |
| SCHEMBL2292858 | 0.88 | KDM4E (0.39) | HSP90AA1HSP90AB1NPSR1ALDH1A1CYP1A2 | |
| SCHEMBL3752163 | 0.84 | ITGB1 (0.33) | HSP90AA1HSP90AB1CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL2286974 | 0.84 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1NPSR1CYP3A4CYP2D6 | |
| SCHEMBL2286121 | 0.84 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1NPSR1CYP3A4CYP2D6 | |
| SCHEMBL3747719 | 0.83 | ALDH1A1 (0.33) | CTSANPC1ALDH1A1RAB9A | |
| SCHEMBL2286995 | 0.83 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1NPSR1CYP3A4CYP2D6 | |
| SCHEMBL3746106 | 0.83 | ALDH1A1 (0.33) | CTSANPC1ALDH1A1RAB9A | |
| SCHEMBL2287015 | 0.83 | CYP3A4 (0.31) | HSP90AA1HSP90AB1NPSR1CYP3A4CYP2D6 | |
| SCHEMBL2289444 | 0.83 | EDNRB (0.39) | CTSANPC1ALDH1A1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773124-B1 | A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE | BAYER CROPSCIENCE AG (DE) | 2012-08-22 | — | — | EP | disclosed |
| US-8008484-B2 | Use of sulfonanilides as agricultural and horticultural fungicide | BAYER CROPSCIENCE AG (DE) | 2011-08-30 | — | — | US | disclosed |
| US-7829703-B2 | Difluoromethanesulfonyl anilide derivatives useful as herbicides | BAYER CROPSCIENCE AG (DE) | 2010-11-09 | — | — | US | disclosed |
| US-7482308-B2 | Difluoromethanesulfonyl anilide derivatives useful as herbicides | BAYER CROPSCIENCE AG (DE) | 2009-01-27 | — | — | US | disclosed |
| US-20080312084-A1 | DIFLUOROMETHANESFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-12-18 | — | — | US | disclosed |
| US-20070219199-A1 | Use of Sulfonanilides as Agricultural and Horticultural Fungicide | BAYER CROPSCIENCE AG (DE) | 2007-09-20 | — | — | US | disclosed |
| US-20070197390-A1 | Difluoromethanesulfonyl anilide derivatives useful as herbicides | BAYER CROPSCIENCE AG (DE) | 2007-08-23 | — | — | US | disclosed |
| EP-1750510-B1 | DIFLUOROMETHANESULFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2007-08-22 | — | — | EP | disclosed |
| EP-1773124-A1 | A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE | Bayer CropScience Aktiengesellschaft (DE) | 2007-04-18 | — | — | EP | disclosed |
| EP-1750510-A1 | DIFLUOROMETHANESULFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES | Bayer CropScience AG (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2006008159-A1 | A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE | BAYER CROPSCIENCE AG (DE) | 2006-01-26 | — | — | WO | disclosed |
| WO-2005096818-A1 | DIFLUOROMETHANESULFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219199-A1 | Use of Sulfonanilides as Agricultural and Horticultural Fungicide | CBR3, CYP51A1, CBR1 | HSP90AA1 3876/4885HSP90AB1 3783/4885NPSR1 197/4885 |
| US-20070197390-A1 | Difluoromethanesulfonyl anilide derivatives useful as herbicides | PFAS, DDT, HDHD5 | HSP90AA1 516/4885HSP90AB1 347/4885NPSR1 1844/4885 |
| US-20080312084-A1 | DIFLUOROMETHANESFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES | HDHD5, PFAS, DDT | HSP90AA1 658/4885HSP90AB1 435/4885NPSR1 2060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.