Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 10/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874836 | 0.87 | AOC3 (0.49) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4874841 | 0.87 | AOC3 (0.49) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3932528 | 0.87 | AOC3 (0.50) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3936307 | 0.87 | AOC3 (0.50) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL6264653 | 0.87 | AOC3 (0.50) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3932522 | 0.87 | AOC3 (0.50) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL6264646 | 0.87 | AOC3 (0.50) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3939275 | 0.85 | AOC3 (0.49) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3939278 | 0.85 | AOC3 (0.49) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3941424 | 0.85 | AOC3 (0.49) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786792-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | Astellas Pharma Inc. (JP) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006011631-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | ASTELLAS PHARMA INC. (JP) | 2006-02-02 | — | — | WO | disclosed |