Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 14/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264646 | 1.00 | AOC3 (0.50) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4874841 | 0.91 | AOC3 (0.49) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4874836 | 0.91 | AOC3 (0.49) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3932528 | 0.90 | AOC3 (0.50) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3936307 | 0.90 | AOC3 (0.50) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3932522 | 0.90 | AOC3 (0.50) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3939278 | 0.87 | AOC3 (0.49) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3939275 | 0.87 | AOC3 (0.49) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5503174 | 0.87 | AOC3 (0.49) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3941424 | 0.87 | AOC3 (0.49) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608365-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | Sucampo AG (CH) | 2005-12-28 | — | — | EP | disclosed |
| EP-1587800-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS | Astellas Pharma Inc. (JP) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004087138-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | SUCAMPO AG (CH) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004067521-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-08-12 | — | — | WO | disclosed |