Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | SDHA | P31040 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CALML3 | P27482 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 4/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5112524 | 1.00 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5112531 | 1.00 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5110956 | 0.91 | MAOB (0.47) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5518390 | 0.91 | MAOB (0.46) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5110962 | 0.91 | MAOB (0.47) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5518383 | 0.91 | MAOB (0.46) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5113218 | 0.89 | MAOA (0.59) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5113213 | 0.89 | MAOA (0.59) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5112263 | 0.88 | F10 (0.47) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5112274 | 0.88 | F10 (0.47) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781643-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016220-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |