Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.60 |
| ▸ | TK1 | P04183 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | VCP | P55072 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | HPRT1 | P00492 | 10/20 | 0.59 |
| ▸ | HBB | P68871 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | EDNRA | P25101 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20723337 | 0.90 | PNP (0.60) | PNPTK1BLMMEN1KMT2A | |
| SCHEMBL7262066 | 0.89 | HPRT1 (0.61) | PNPTK1BLMMEN1KMT2A | |
| SCHEMBL7262060 | 0.89 | HPRT1 (0.61) | PNPTK1BLMMEN1KMT2A | |
| SCHEMBL7268685 | 0.89 | HPRT1 (0.61) | PNPTK1BLMMEN1KMT2A | |
| SCHEMBL24420130 | 0.88 | PNP (0.56) | PNPTK1BLMMEN1KMT2A | |
| SCHEMBL26779929 | 0.88 | PNP (0.56) | PNPTK1BLMMEN1KMT2A | |
| SCHEMBL26779932 | 0.88 | PNP (0.56) | PNPTK1BLMMEN1KMT2A | |
| SCHEMBL8097057 | 0.86 | PNP (0.60) | PNPTK1BLMMEN1KMT2A | |
| SCHEMBL15054517 | 0.85 | HPRT1 (0.57) | PNPTK1BLMMEN1KMT2A | |
| SCHEMBL27054012 | 0.84 | PNP (0.53) | PNPTK1BLMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977767-B1 | AMINOOXY-MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2007-09-19 | — | — | EP | claimed |
| JP-60199899-A | — | — | None | — | — | JP | disclosed |
| CN-109536442-B | Separation method of placenta mesenchymal stem cells | 青岛奥克生物开发有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-20240066047-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-02-29 | — | — | US | disclosed |
| US-20210137962-A9 | CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-05-13 | — | — | US | disclosed |
| US-10980825-B2 | Cyclic dinucleotide | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-04-20 | — | — | US | disclosed |
| US-20190192549-A1 | CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICALS CO (JP) | 2019-06-27 | — | — | US | disclosed |
| JP-S60199899-A | NUCLEOSIDE 3'-PHOSPHOTRIESTER DERIVATIVE | FUJIREBIO INC | 1985-10-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066047-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE | STING1, TLR9, CGAS | PNP 174/4885TK1 216/4885BLM 106/4885 |
| US-20210137962-A9 | CYCLIC DINUCLEOTIDE | STING1, CGAS, MAVS | PNP 138/4885TK1 240/4885BLM 45/4885 |
| US-10980825-B2 | Cyclic dinucleotide | STING1, CGAS, MAVS | PNP 138/4885TK1 240/4885BLM 45/4885 |
| US-20190192549-A1 | CYCLIC DINUCLEOTIDE | STING1, CGAS, MAVS | PNP 138/4885TK1 240/4885BLM 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.