Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4175939 | 0.90 | AR (0.66) | ARALDH1A1GAASLC22A12PGR | |
| SCHEMBL4188869 | 0.86 | AR (0.67) | ARALDH1A1SLC22A12L3MBTL1PGR | |
| SCHEMBL2354199 | 0.81 | ALDH1A1 (0.62) | ARALDH1A1GAAL3MBTL1 | |
| SCHEMBL9502758 | 0.78 | ALDH1A1 (0.48) | ARALDH1A1GAA | |
| SCHEMBL4175953 | 0.77 | AR (1.00) | ARGAASLC22A12PGR | |
| SCHEMBL8543199 | 0.76 | AR (0.62) | ARALDH1A1GAASLC22A12PGR | |
| SCHEMBL13890551 | 0.75 | AR (0.75) | ARGAASLC22A12 | |
| SCHEMBL753907 | 0.75 | AR (0.75) | ARGAASLC22A12PGR | |
| SCHEMBL30426714 | 0.75 | AR (0.66) | ARALDH1A1GAAL3MBTL1 | |
| SCHEMBL4184922 | 0.75 | AR (0.65) | ARALDH1A1SLC22A12PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781280-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018723-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-02-23 | — | — | WO | disclosed |