Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170196 | 0.89 | AR (0.58) | ARSLC22A12SLC6A4ESRRAMAPT | |
| SCHEMBL4175734 | 0.87 | AR (0.59) | ARSLC22A12SLC6A4ESRRANR3C1 | |
| SCHEMBL4179847 | 0.80 | AR (0.68) | ARSLC6A4ESRRAMAPTL3MBTL1 | |
| SCHEMBL4184976 | 0.80 | AR (0.62) | ARSLC6A4ESRRAMAPTL3MBTL1 | |
| SCHEMBL4183157 | 0.76 | AR (0.73) | ARSLC22A12SLC6A4ESRRAMAPT | |
| SCHEMBL435768 | 0.75 | TRPV4 (0.56) | ARSLC6A4MAPTL3MBTL1RAB9A | |
| SCHEMBL5498082 | 0.75 | AR (0.64) | ARSLC6A4ESRRAMAPTL3MBTL1 | |
| SCHEMBL16640622 | 0.75 | AR (0.54) | ARSLC22A12SLC6A4ESRRASCN8A | |
| SCHEMBL4181543 | 0.73 | AR (0.73) | ARSLC6A4ESRRAALDH1A1SLC6A3 | |
| SCHEMBL4188134 | 0.73 | AR (0.73) | ARSLC22A12SLC6A4ESRRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781280-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018723-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-02-23 | — | — | WO | disclosed |