Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2456062 | 0.98 | DGAT1 (0.53) | DGAT1TSHRMEN1KMT2AMAPT | |
| SCHEMBL22950515 | 0.86 | DGAT1 (0.54) | DGAT1TSHRMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL21632724 | 0.85 | DGAT1 (0.53) | DGAT1TSHRMEN1KMT2AMAPT | |
| SCHEMBL6578363 | 0.84 | DGAT1 (0.59) | DGAT1TSHRMAPTSMN1; SMN2LMNA | |
| SCHEMBL10040527 | 0.84 | DGAT1 (0.50) | DGAT1TSHRMEN1KMT2AMAPT | |
| SCHEMBL15007064 | 0.82 | DGAT1 (0.49) | DGAT1MEN1KMT2AMAPTCASP3 | |
| Hydrochloric Acid SCHEMBL3130867 | 0.82 | DGAT1 (0.49) | DGAT1TSHRMEN1KMT2AMAPT | |
| SCHEMBL3733983 | 0.82 | DGAT1 (0.57) | DGAT1TSHRMAPTSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL6578358 | 0.82 | DGAT1 (0.57) | DGAT1TSHRMAPTSMN1; SMN2LMNA | |
| SCHEMBL1146528 | 0.81 | CA12 (0.56) | MEN1KMT2AMAPTCASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861380-A1 | 2-(4-OXO-4H-QUINAZOLIN-3-YL)ACETAMIDES AND THEIR USE AS VASOPRESSIN V3 ANTAGONISTS | N.V. Organon (NL) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006095014-A1 | 2- (4-0X0-4H-QUINAZ0LIN-3-YL) ACETAMIDES AND THEIR USE AS VASOPRESSIN V3 ANTAGONISTS | N.V. ORGANON (NL) | 2006-09-14 | — | — | WO | disclosed |