Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 18/20 | 0.37 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | LITAF | Q99732 | 2/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72926 | 0.80 | PDE4D (0.37) | PDE9APDE1C | |
| SCHEMBL3873741 | 0.76 | PDE4B (0.36) | — | |
| SCHEMBL84902 | 0.73 | PDE4D (0.54) | — | |
| SCHEMBL3872957 | 0.71 | MAPT (0.35) | PDE9A | |
| SCHEMBL29703260 | 0.63 | GAA (0.47) | PDE9APDE1C | |
| SCHEMBL5501126 | 0.61 | ADORA2A (0.39) | — | |
| SCHEMBL30881895 | 0.60 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL28282726 | 0.57 | ADRA1A (0.39) | — | |
| SCHEMBL10670636 | 0.56 | BRD4 (0.45) | PDE9A | |
| SCHEMBL9828687 | 0.56 | CNR2 (0.60) | PDE9APDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831227-A2 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | Glenmark Pharmaceuticals S.A. (CH) | 2007-09-12 | — | — | EP | claimed |
| WO-2006064355-A2 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-06-22 | — | — | WO | claimed |