Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540873 | 0.91 | KDM4E (0.42) | KDM4EL3MBTL1MAPTPOLBMEN1 | |
| SCHEMBL5573437 | 0.89 | KDM4E (0.38) | KDM4EL3MBTL1MAPTPOLBMEN1 | |
| SCHEMBL5574783 | 0.88 | KDM4E (0.44) | KDM4EL3MBTL1MAPTPOLBMEN1 | |
| SCHEMBL5571405 | 0.87 | KDM4E (0.43) | KDM4EL3MBTL1MAPTPOLBMEN1 | |
| SCHEMBL5574005 | 0.86 | KDM4E (0.43) | KDM4EL3MBTL1MAPTPOLBMEN1 | |
| SCHEMBL5571417 | 0.86 | KDM4E (0.43) | KDM4EL3MBTL1MAPTPOLBMEN1 | |
| SCHEMBL5571402 | 0.86 | KDM4E (0.43) | KDM4EL3MBTL1MAPTPOLBMEN1 | |
| SCHEMBL5570203 | 0.86 | KDM4E (0.43) | KDM4EL3MBTL1MAPTPOLBMEN1 | |
| SCHEMBL5571416 | 0.86 | MLYCD (0.38) | KDM4EL3MBTL1MLYCDPOLBMEN1 | |
| SCHEMBL5574197 | 0.84 | KDM4E (0.41) | KDM4EL3MBTL1MAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |