SCHEMBL5504563

SCHEMBL5504563

CCCCC(N)c1ncco1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.37
FAAH O00519 2/20 0.36
CES1 P23141 1/20 0.36
CA2 P00918 1/20 0.33
LNPEP Q9UIQ6 1/20 0.30
BDKRB2 P30411 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27336909 0.81 FAAH (0.38) FAAHCES1BDKRB2
SCHEMBL26646510 0.80 FAAH (0.37) FAAHCES1BDKRB2
SCHEMBL14764834 0.79 FAAH (0.36) FAAHCES1BDKRB2
SCHEMBL27791138 0.79 FAAH (0.36) FAAHCES1BDKRB2
SCHEMBL26646458 0.79 FAAH (0.36) FAAHCES1BDKRB2
SCHEMBL20098073 0.77 FAAH (0.41) SLC2A1FAAHCES1
SCHEMBL24814189 0.76 FAAH (0.45) FAAHCES1
SCHEMBL20893257 0.75 FAAH (0.42) SLC2A1FAAHCES1
SCHEMBL22166109 0.75 FAAH (0.42) SLC2A1FAAHCES1
SCHEMBL22692970 0.75 FAAH (0.42) SLC2A1FAAHCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1758654-A1 USE OF C-KIT INHIBITORS FOR TREATING PLASMODIUM RELATED DISEASES AB Science (FR) 2007-03-07 EP disclosed
WO-2005102455-A1 USE OF C-KIT INHIBITORS FOR TREATING PLASMODIUM RELATED DISEASES AB SCIENCE (FR) 2005-11-03 WO disclosed