Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.38 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81663 | 1.00 | HPGD (0.41) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL2294175 | 1.00 | HPGD (0.41) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL2294029 | 0.90 | GRM2 (0.43) | GRM2MEN1KMT2AALDH1A1MMP1 | |
| SCHEMBL2296357 | 0.90 | GRM2 (0.43) | GRM2MEN1KMT2AALDH1A1MMP1 | |
| SCHEMBL2297561 | 0.89 | CYP3A4 (0.40) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2295657 | 0.89 | CYP3A4 (0.40) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2293903 | 0.88 | TDP1 (0.42) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL2296066 | 0.88 | TDP1 (0.42) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL2291329 | 0.86 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2295340 | 0.86 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789414-A1 | 2-MORPHOLINO-4-PYRIMIDONE COMPOUND | Mitsubishi Pharma Corporation (JP) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006028290-A1 | 2-MORPHOLINO-4-PYRIMIDONE COMPOUND | MITSUBISHI PHARMA CORPORATION (JP) | 2006-03-16 | — | — | WO | disclosed |