Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 20/20 | 0.71 |
| ▸ | KLKB1 | P03952 | 18/20 | 0.71 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393593 | 0.83 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL393592 | 0.83 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL393927 | 0.79 | F11 (0.66) | F11KLKB1 | |
| SCHEMBL12606833 | 0.63 | CYP3A4 (0.47) | — | |
| SCHEMBL19191290 | 0.63 | F11 (0.44) | F11KLKB1 | |
| SCHEMBL13973860 | 0.61 | ATM (0.46) | F11KLKB1 | |
| SCHEMBL2331896 | 0.61 | F11 (0.70) | F11KLKB1 | |
| SCHEMBL2325164 | 0.61 | F11 (0.70) | F11KLKB1 | |
| SCHEMBL11188191 | 0.60 | F11 (0.42) | F11KLKB1 | |
| SCHEMBL391514 | 0.59 | F11 (0.66) | F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773786-A2 | FIVE-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2005123050-A2 | FIVE-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-12-29 | — | — | WO | disclosed |