Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846448 | 0.90 | REN (0.64) | RENCYP3A4 | |
| SCHEMBL2846452 | 0.90 | REN (0.64) | RENCYP3A4 | |
| SCHEMBL1861558 | 0.90 | REN (0.64) | RENCYP3A4 | |
| SCHEMBL1861560 | 0.90 | REN (0.64) | RENCYP3A4 | |
| SCHEMBL4755380 | 0.89 | REN (0.68) | RENCYP3A4 | |
| SCHEMBL1863848 | 0.89 | REN (0.68) | RENCYP3A4 | |
| SCHEMBL4298773 | 0.85 | REN (0.65) | REN | |
| SCHEMBL4292054 | 0.85 | REN (0.65) | REN | |
| SCHEMBL4292048 | 0.85 | REN (0.65) | REN | |
| SCHEMBL1865004 | 0.85 | REN (0.84) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807078-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006042150-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |