SCHEMBL5504881

SCHEMBL5504881

CC(CF)N1C(=O)Cc2cc(N3CC(C(N)=O)OC3=O)ccc21

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 8/20 0.47
MAOB P27338 8/20 0.35
CALML3 P27482 2/20 0.35
LMNA P02545 1/20 0.35
PTGS1 P23219 1/20 0.35
SDHA P31040 1/20 0.35
F10 P00742 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5504875 1.00 MAOA (0.47) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5509315 0.91 MAOA (0.45) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL20990238 0.91 MAOA (0.45) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5515235 0.91 MAOA (0.45) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5518036 0.89 MAOA (0.37) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5518044 0.89 MAOA (0.37) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL20989998 0.89 MAOA (0.48) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5504072 0.89 MAOA (0.48) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5121418 0.85 F10 (0.45) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5120654 0.85 F10 (0.45) MAOAMAOBCALML3LMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060030609-A1 Oxazolidinones containing oxindoles as antibacterial agents LUEHR GARY W 2006-02-09 US claimed
EP-1781642-A1 OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS Pharmacia & Upjohn Company LLC (US) 2007-05-09 EP disclosed
WO-2006016221-A1 OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-02-16 WO disclosed
US-20060030609-A1 Oxazolidinones containing oxindoles as antibacterial agents LUEHR GARY W 2006-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060030609-A1 Oxazolidinones containing oxindoles as antibacterial agents OXA1L, OXSR1, OXER1 MAOA 766/4885MAOB 707/4885CALML3 2427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.