1,6-Hexanediol

1,6-Hexanediol

SCHEMBL5505002

CO.N.OCCCCCCO

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.60
ALDH1A1 P00352 3/20 0.60
LMNA P02545 2/20 0.60
HSD17B10 Q99714 1/20 0.60
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.53
GPR84 Q9NQS5 1/20 0.42
FFAR1 O14842 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
KDM4E B2RXH2 1/20 0.39
MIF P14174 1/20 0.36
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CYP4F2 P78329 2/20 0.32
CYP4A11 Q02928 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
CAMK2A Q9UQM7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,6-Hexanediol SCHEMBL9487678 0.95 TSHR (0.64) TSHRALDH1A1LMNAHSD17B10MEN1
1,5-Pentanediol SCHEMBL7561523 0.95 TSHR (0.64) TSHRALDH1A1LMNAHSD17B10MEN1
Methyl Alcohol SCHEMBL28231208 0.95 TSHR (0.64) TSHRALDH1A1LMNAHSD17B10MEN1
1,6-Hexanediol SCHEMBL28160475 0.91
1,5-Pentanediol SCHEMBL28135610 0.91
1,4-Butanediol SCHEMBL10709999 0.91
1,6-Hexanediol SCHEMBL1726467 0.91 TSHR (0.57) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL25302278 0.85 TSHR (0.61) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL21462773 0.85 TSHR (0.61) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL2355465 0.85 TSHR (0.61) TSHRALDH1A1LMNAHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1830970-A2 METHOD OF APPLYING AUTOMOTIVE PRIMER-SURFACER USING A SQUEEGEE The Sherwin-Williams Company (US) 2007-09-12 EP disclosed
WO-2006071695-A2 METHOD OF APPLYING AUTOMOTIVE PRIMER-SURFACER USING A SQUEEGEE THE SHERWIN-WILLIAMS COMPANY (US) 2006-07-06 WO disclosed