Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 6/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4477334 | 0.87 | F10 (0.59) | F10ARHTT | |
| SCHEMBL5503712 | 0.86 | F10 (0.38) | F10ARNPY2R | |
| SCHEMBL5510944 | 0.85 | F10 (0.38) | F10ARNPY2R | |
| SCHEMBL5507256 | 0.83 | F10 (0.39) | F10ARNPY2R | |
| SCHEMBL5504066 | 0.79 | F10 (0.46) | F10ARCNR2CNR1NPY2R | |
| SCHEMBL5517405 | 0.77 | F10 (0.40) | F10ARCNR2NPY2R | |
| SCHEMBL5505635 | 0.77 | F10 (0.45) | F10ARNPY2R | |
| SCHEMBL5505524 | 0.76 | F10 (0.40) | F10ARNPY2R | |
| SCHEMBL5504077 | 0.76 | F10 (0.42) | F10ARNPY2R | |
| SCHEMBL5512209 | 0.75 | F10 (0.66) | F10ARCNR2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |