Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501928 | 0.86 | NPC1 (0.33) | NPC1RAB9ACYP1A2 | |
| SCHEMBL5503160 | 0.86 | HSP90AA1 (0.36) | NPC1RAB9AALDH1A1 | |
| SCHEMBL5497135 | 0.85 | NPC1 (0.35) | NPC1RAB9ACYP1A2EDNRBEDNRA | |
| SCHEMBL5502210 | 0.81 | CHRM4 (0.32) | ADORA1 | |
| SCHEMBL5499313 | 0.79 | NPC1 (0.35) | NPC1RAB9ACYP1A2EDNRBEDNRA | |
| SCHEMBL2285840 | 0.77 | NPC1 (0.34) | NPC1RAB9ACYP1A2EDNRBEDNRA | |
| SCHEMBL2283366 | 0.77 | PDE2A (0.39) | NPC1RAB9ACYP1A2EDNRBEDNRA | |
| SCHEMBL2288861 | 0.76 | NPC1 (0.35) | NPC1RAB9ACYP1A2EDNRBEDNRA | |
| SCHEMBL5497132 | 0.74 | EDNRB (0.37) | NPC1RAB9ACYP1A2EDNRBEDNRA | |
| SCHEMBL5505122 | 0.74 | EDNRB (0.34) | NPC1RAB9ACYP1A2EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773124-A1 | A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE | Bayer CropScience Aktiengesellschaft (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006008159-A1 | A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE | BAYER CROPSCIENCE AG (DE) | 2006-01-26 | — | — | WO | disclosed |