Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2283366 | 0.87 | PDE2A (0.39) | NPC1RAB9ACYP1A2ALDH1A1PDE2A | |
| SCHEMBL5502750 | 0.84 | NPC1 (0.33) | NPC1RAB9ACYP1A2CXCR2DHFR | |
| SCHEMBL5501324 | 0.83 | HSP90AA1 (0.38) | NPC1RAB9AALDH1A1DHFRPDE2A | |
| SCHEMBL5501773 | 0.81 | MEN1 (0.38) | RAB9AALDH1A1KDM4ETAAR1 | |
| SCHEMBL2292191 | 0.80 | SLC6A3 (0.41) | NPC1RAB9ACYP1A2ALDH1A1PDE2A | |
| SCHEMBL5504209 | 0.79 | TAAR1 (0.35) | NPC1RAB9AADORA1KDM4EHPGD | |
| SCHEMBL5505124 | 0.79 | NPC1 (0.33) | NPC1RAB9ACYP1A2CXCR2ALDH1A1 | |
| SCHEMBL2285461 | 0.77 | GAA (0.41) | NPC1RAB9ACYP1A2PDE2AADORA2A | |
| SCHEMBL5497135 | 0.76 | NPC1 (0.35) | NPC1RAB9ACYP1A2CXCR2ALDH1A1 | |
| SCHEMBL2289031 | 0.73 | EDNRB (0.35) | NPC1RAB9ACYP1A2ALDH1A1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773124-A1 | A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE | Bayer CropScience Aktiengesellschaft (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006008159-A1 | A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE | BAYER CROPSCIENCE AG (DE) | 2006-01-26 | — | — | WO | disclosed |