Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508082 | 0.81 | KDM4E (0.36) | MAPTALDH1A1KDM4E | |
| SCHEMBL6001496 | 0.80 | AR (0.33) | ALDH1A1CDK1KDM4E | |
| SCHEMBL5505517 | 0.76 | PAK4 (0.40) | MAPTTSHRTDP1KMT2AALDH1A1 | |
| SCHEMBL5509091 | 0.76 | PDPK1 (0.35) | — | |
| SCHEMBL5507028 | 0.72 | POLB (0.34) | MAPTTSHRTDP1ALDH1A1CDK1 | |
| SCHEMBL4951437 | 0.69 | CDK1 (0.38) | MAPTTSHRTDP1KMT2AALDH1A1 | |
| SCHEMBL5507479 | 0.68 | PTGER4 (0.33) | — | |
| SCHEMBL5500602 | 0.67 | TSHR (0.39) | MAPTTSHRTDP1CDK1TNIK | |
| SCHEMBL5507645 | 0.67 | IKBKB (0.41) | MAPTKMT2AALDH1A1ADORA2AADORA1 | |
| SCHEMBL24819183 | 0.66 | PI4KA (0.34) | MAPTTSHRTDP1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846108-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4,7-DIAMINES, AND USE THEREOF | The Procter & Gamble Company (US) | 2007-10-24 | — | — | EP | claimed |
| WO-2006078800-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4-, 7-DIAMINES, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-27 | — | — | WO | claimed |
| US-20060162099-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2006-07-27 | — | — | US | claimed |
| EP-1846108-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4,7-DIAMINES, AND USE THEREOF | The Procter & Gamble Company (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006078800-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4-, 7-DIAMINES, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-27 | — | — | WO | disclosed |
| US-20060162099-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060162099-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, DSP, KRTCAP2 | MAPT 191/4885TSHR 4837/4885TDP1 2779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.