Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231174 | 0.89 | TLR7 (0.53) | TLR7ADORA2APDE4DLMNAPOLB | |
| Epetirimod SCHEMBL4178900 | 0.80 | TLR7 (0.61) | TLR7ADORA2APDE4DLMNAPOLB | |
| Epetirimod SCHEMBL4985288 | 0.80 | TLR7 (0.61) | TLR7ADORA2APDE4DLMNAPOLB | |
| Epetirimod SCHEMBL4983116 | 0.79 | TLR7 (0.60) | TLR7ADORA2APDE4DLMNAPOLB | |
| Epetirimod SCHEMBL4178322 | 0.79 | TLR7 (0.60) | TLR7ADORA2APDE4DLMNAPOLB | |
| Imiquimod SCHEMBL9602249 | 0.76 | TLR7 (0.82) | TLR7ADORA2APDE4DLMNAPOLB | |
| Epetirimod SCHEMBL29350668 | 0.75 | TLR7 (0.70) | TLR7ADORA2APDE4DLMNAPOLB | |
| Epetirimod SCHEMBL544542 | 0.75 | TLR7 (0.70) | TLR7ADORA2APDE4DLMNAPOLB | |
| Epetirimod SCHEMBL29454521 | 0.75 | TLR7 (0.70) | TLR7ADORA2APDE4DLMNAPOLB | |
| SCHEMBL3862504 | 0.72 | TLR7 (0.73) | TLR7ADORA2APDE4DLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833479-A2 | 1-(2-METHYLPROPYL)-1H-IMIDAZO 4,5-C(1,5 )NAPHTHYRIDIN-4-AMINE ETHANESULFONATE AND 1-(2-METHYLPROPYL)-1H-IMIDAZOÝ4,5-C 1,5 NAPHTHYRIDIN-4-AMINE METHANESULFONATE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-19 | — | — | EP | disclosed |