⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5512232 | 0.97 | OPRM1 (0.52) | — | |
| SCHEMBL5509935 | 0.97 | OPRM1 (0.52) | — | |
| SCHEMBL7900423 | 0.90 | — | — | |
| SCHEMBL8081659 | 0.84 | — | — | |
| SCHEMBL50698 | 0.84 | — | — | |
| SCHEMBL50481 | 0.81 | — | — | |
| SCHEMBL8074338 | 0.81 | — | — | |
| SCHEMBL3620831 | 0.81 | LCK (0.56) | — | |
| SCHEMBL8422502 | 0.81 | — | — | |
| SCHEMBL1882258 | 0.81 | LCK (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157442-B2 | Antibacterial compound | SANKYO COMPANY, LIMITED (JP) | 2007-01-02 | — | — | US | disclosed |
| EP-1209166-B1 | NOVEL A-500359 DERIVATIVES | SANKYO CO (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-20030171330-A1 | Antibacterial compound | SANKYO COMPANY, LIMITED (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1209166-A1 | NOVEL A-500359 DERIVATIVES | Sankyo Company, Limited (JP) | 2002-05-29 | — | — | EP | disclosed |