Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL390932 | 0.99 | DRD2 (0.58) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL388264 | 0.89 | DRD2 (0.55) | DRD2DRD3 | |
| SCHEMBL6179407 | 0.89 | DRD2 (0.60) | DRD2DRD3 | |
| SCHEMBL390840 | 0.89 | DRD2 (0.60) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL388283 | 0.88 | DRD2 (0.59) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL393384 | 0.88 | DRD2 (0.59) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL389910 | 0.86 | DRD2 (0.60) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL393405 | 0.85 | DRD2 (0.45) | DRD2DRD3 | |
| SCHEMBL4389023 | 0.85 | DRD3 (0.48) | DRD2DRD3 | |
| SCHEMBL7452459 | 0.85 | DRD3 (0.59) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817037-A1 | TRIAZOLE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULAIONT OF THE DOPAMINE D3 RECEPTOR | Abbott GmbH & Co. KG (DE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006058753-A1 | TRIAZOLE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULAIONT OF THE DOPAMINE D3 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2006-06-08 | — | — | WO | disclosed |