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SCHEMBL5505809

SCHEMBL5505809

CC(=O)SCc1cccc(-c2c3nc(c(-c4cccc(I)c4)c4ccc([nH]4)c(-c4cccc(CSC(C)=O)c4)c4nc(c(-c5cccc(I)c5)c5ccc2[nH]5)C=C4)C=C3)c1.[Zn]

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 4/20 0.39
▸ CYCS P99999 4/20 0.39
▸ TERT O14746 4/20 0.37
▸ ABCG2 Q9UNQ0 1/20 0.36
▸ ENPP2 Q13822 1/20 0.36
▸ MAOB P27338 1/20 0.33
▸ STAT3 P40763 1/20 0.33
▸ STAT1 P42224 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5503173 0.98 TOP1 (0.39) TOP1CYCSTERTABCG2ENPP2
SCHEMBL5510888 0.98 TOP1 (0.39) TOP1CYCSTERTABCG2ENPP2
SCHEMBL4261959 0.94 TOP1 (0.44) TOP1CYCSTERTABCG2ENPP2
SCHEMBL4260949 0.92 TOP1 (0.45) TOP1CYCSTERTABCG2ENPP2
SCHEMBL4266260 0.91 TOP1 (0.44) TOP1CYCSTERTABCG2ENPP2
SCHEMBL5502125 0.81 TERT (0.36) TOP1CYCSTERTENPP2MAOB
SCHEMBL16247124 0.74 TOP1 (0.45) TOP1CYCSTERTABCG2ENPP2
SCHEMBL4274586 0.73 TERT (0.40) TOP1CYCSTERTENPP2STAT3
SCHEMBL8908306 0.73 TOP1 (0.48) TOP1CYCSTERTABCG2ENPP2
SCHEMBL8909228 0.73 GRIN2D (0.53) TOP1CYCSTERTABCG2ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1282464-A4 HIGH-DENSITY NON-VOLATILE MEMORY DEVICES INCORPORATING THIOL-DERIVATIZED PORPHYRIN TRIMERS UNIV NORTH CAROLINA STATE (US) 2007-10-24 — — EP disclosed
EP-1282464-A2 HIGH-DENSITY NON-VOLATILE MEMORY DEVICES INCORPORATING THIOL-DERIVATIZED PORPHYRIN TRIMERS NORTH CAROLINA STATE UNIVERSITY (US) 2003-02-12 — — EP disclosed
US-6272038-B1 High-density non-volatile memory devices incorporating thiol-derivatized porphyrin trimers NORTH CAROLINA STATE UNIVERSITY 2001-08-07 — — US disclosed
WO-2001051188-A2 HIGH-DENSITY NON-VOLATILE MEMORY DEVICES INCORPORATING THIOL-DERIVATIZED PORPHYRIN TRIMERS NORTH CAROLINA STATE UNIVERSITY (US) 2001-07-19 — — WO disclosed
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