Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504137 | 0.99 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBCCNA2 | |
| SCHEMBL5507611 | 0.91 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBCCNA2 | |
| SCHEMBL5507476 | 0.86 | ADORA2A (0.56) | ADORA3ADORA2AADORA2B | |
| SCHEMBL5506455 | 0.86 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL5506522 | 0.85 | ADORA2A (0.55) | ADORA3ADORA1ADORA2AADORA2BRXFP1 | |
| SCHEMBL5996922 | 0.85 | ADORA2A (0.55) | ADORA3ADORA1ADORA2AADORA2BRXFP1 | |
| SCHEMBL5503630 | 0.85 | ADORA2A (0.55) | ADORA3ADORA1ADORA2AADORA2BRXFP1 | |
| SCHEMBL5510529 | 0.85 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL5512560 | 0.84 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBCCNA2 | |
| SCHEMBL5506216 | 0.84 | ADORA2A (0.52) | ADORA3ADORA1ADORA2AADORA2BRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537133-B1 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | CV THERAPEUTICS INC (US) | 2007-07-25 | — | — | EP | disclosed |