Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506328 | 0.99 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL5507611 | 0.92 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL5506522 | 0.86 | ADORA2A (0.55) | ADORA3ADORA1ADORA2AADORA2BRXFP1 | |
| SCHEMBL5503630 | 0.86 | ADORA2A (0.55) | ADORA3ADORA1ADORA2AADORA2BRXFP1 | |
| SCHEMBL5996922 | 0.86 | ADORA2A (0.55) | ADORA3ADORA1ADORA2AADORA2BRXFP1 | |
| SCHEMBL5510529 | 0.85 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL5507476 | 0.85 | ADORA2A (0.56) | ADORA3ADORA2AADORA2B | |
| SCHEMBL5506455 | 0.85 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL5506216 | 0.84 | ADORA2A (0.52) | ADORA3ADORA1ADORA2AADORA2BRXFP1 | |
| SCHEMBL5503372 | 0.84 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537133-B1 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | CV THERAPEUTICS INC (US) | 2007-07-25 | — | — | EP | disclosed |
| US-20060135467-A1 | Partial and full agonists of A1 adenosine receptors | ZABLOCKI JEFF | 2006-06-22 | — | — | US | disclosed |
| US-7022681-B2 | Partial and full agonists of A1 adenosine receptors | CV THERAPEUTICS, INC. (US) | 2006-04-04 | — | — | US | disclosed |
| US-20040043960-A1 | Partial and full agonists of A1 adenosine receptors | CV THERAPEUTICS, INC. | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135467-A1 | Partial and full agonists of A1 adenosine receptors | ADORA1, ADORA2A, ADORA3 | PI4KA 1835/4885PI4K2B 3445/4885PI4K2A 2297/4885 |
| US-20040043960-A1 | Partial and full agonists of A1 adenosine receptors | ADORA1, ADORA2A, ADORA3 | PI4KA 1901/4885PI4K2B 3579/4885PI4K2A 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.