Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.41 |
| ▸ | FABP7 | O15540 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543987 | 0.78 | ALDH1A1 (0.51) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL10167010 | 0.69 | EPHX2 (0.47) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL29381061 | 0.67 | FABP5 (0.59) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL29901230 | 0.67 | FABP5 (0.59) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL44677 | 0.67 | FABP5 (0.59) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL30179376 | 0.66 | MDM4 (0.46) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL1157518 | 0.66 | ALDH1A1 (0.45) | FABP5FABP7KMT2AMDM4TP53 | |
| SCHEMBL29362617 | 0.65 | KMT2A (0.59) | FABP5FABP7KMT2AHSD17B10EPHX2 | |
| SCHEMBL113270 | 0.65 | KMT2A (0.59) | FABP5FABP7KMT2AHSD17B10EPHX2 | |
| SCHEMBL30042128 | 0.65 | KMT2A (0.59) | FABP5FABP7KMT2AHSD17B10EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778718-A1 | INHIBITORS OF IAP | Genentech, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006014361-A1 | INHIBITORS OF IAP | GENENTECH, INC. (US) | 2006-02-09 | — | — | WO | disclosed |