Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 1.00 |
| ▸ | CTSL | P07711 | 15/20 | 1.00 |
| ▸ | CTSB | P07858 | 14/20 | 1.00 |
| ▸ | CTSK | P43235 | 10/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818563 | 1.00 | CTSS (1.00) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1273010 | 0.96 | CTSS (0.93) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1271557 | 0.96 | CTSS (0.93) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1273011 | 0.96 | CTSS (0.93) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1272813 | 0.94 | CTSS (0.88) | CTSSCTSLCTSBCTSK | |
| SCHEMBL14324339 | 0.94 | CTSS (0.88) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1272500 | 0.94 | CTSS (0.88) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2395979 | 0.93 | CTSS (0.87) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2395980 | 0.93 | CTSS (0.87) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1271692 | 0.92 | CTSS (0.85) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797032-A1 | POLYMORPHS OF THE CYSTEINE PROTEASE INHIBITOR N-(1-CYANOCYCLOPROPYL)-3-CYCLOPROPYLMETHANESULFONYL-2(R)-[2,2,2-TRIFLUORO-1(S)-(4-FLUOROPHENYL)ETHYLAMINO]PROPIONAMIDE | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006034006-A1 | POLYMORPHS OF THE CYSTEINE PROTEASE INHIBITOR N- (1-CYANOCYCLOPROPYL)-3-CYCLOPROPYLMETHANSULFONYL-2 (R) - (2,2,2-TRIFLUORO-1 (S) - (4-FLUOROPHENYL) ETHYLAMINO) PROPIONAMIDE | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-03-30 | — | — | WO | disclosed |