Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CALML3 | P27482 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SDHA | P31040 | 1/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.33 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | FADS1 | O60427 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504384 | 0.91 | MAOA (0.61) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL5999012 | 0.88 | MAOA (0.50) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3035482 | 0.82 | MAOA (0.59) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3039436 | 0.79 | MAOA (0.46) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3041174 | 0.79 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3046132 | 0.79 | MAOA (0.48) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL5004965 | 0.79 | F10 (0.45) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL14029041 | 0.79 | F10 (0.45) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL5004964 | 0.79 | F10 (0.45) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL5107623 | 0.78 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |