Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.45 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501246 | 0.88 | TAAR1 (0.50) | SLC6A4SLC6A2KCNH2SLC6A3HTR2A | |
| SCHEMBL5506932 | 0.82 | SLC6A4 (0.44) | SLC6A4SLC6A2KCNH2SLC6A3HTR2A | |
| SCHEMBL5501242 | 0.82 | SLC6A4 (0.67) | SLC6A4SLC6A2KCNH2SLC6A3HTR2A | |
| SCHEMBL5501939 | 0.71 | TAAR1 (0.50) | HTR2A | |
| SCHEMBL5498157 | 0.70 | TAAR1 (0.52) | HTR2A | |
| SCHEMBL5501642 | 0.69 | TAAR1 (0.51) | HTR2A | |
| SCHEMBL9921408 | 0.69 | HMGCR (0.47) | SLC6A4SLC6A2KCNH2SLC6A3PTGES2 | |
| Hydrochloric Acid SCHEMBL5457539 | 0.69 | TAAR1 (0.50) | HTR2A | |
| SCHEMBL5502216 | 0.68 | SLC6A4 (0.42) | SLC6A4SLC6A2KCNH2SLC6A3HTR2A | |
| SCHEMBL5498154 | 0.68 | SLC6A4 (0.50) | SLC6A4SLC6A2KCNH2SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791807-A1 | THERAPEUTIC DIPHENYL ETHER LIGANDS | Pfizer Products Incorporated (US) | 2007-06-06 | — | — | EP | claimed |
| WO-2006027684-A1 | THERAPEUTIC DIPHENYL ETHER LIGANDS | PFIZER PRODUCTS INC. (US) | 2006-03-16 | — | — | WO | claimed |