SCHEMBL5506967

SCHEMBL5506967

Cc1c(C(=CC2(c3ccc(N(C)C)cc3)OC(=O)c3ccccc32)c2c(C)n(C)c3ccccc23)c2ccccc2n1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.36
TDP1 Q9NUW8 5/20 0.36
HSD17B10 Q99714 4/20 0.36
HPGD P15428 4/20 0.36
CYP3A4 P08684 3/20 0.36
HIF1A Q16665 1/20 0.36
KDM4E B2RXH2 2/20 0.34
HTT P42858 2/20 0.34
GAA P10253 2/20 0.34
CYP2C19 P33261 2/20 0.34
GLA P06280 1/20 0.34
KMT2A Q03164 10/20 0.34
MEN1 O00255 8/20 0.34
LMNA P02545 5/20 0.33
MAPT P10636 5/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
THRB P10828 1/20 0.32
TP53 P04637 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9416197 0.88 ALDH1A1 (0.34) ALDH1A1TDP1HSD17B10HPGDCYP3A4
SCHEMBL7481955 0.83 MEN1 (0.33) ALDH1A1TDP1HSD17B10HPGDCYP3A4
SCHEMBL20383173 0.81 ALDH1A1 (0.32) ALDH1A1TDP1HPGDCYP3A4HIF1A
SCHEMBL7482470 0.80 SRD5A1 (0.32) ALDH1A1TDP1HSD17B10HPGDCYP3A4
SCHEMBL6949531 0.80 ALDH1A1 (0.46) ALDH1A1TDP1HSD17B10HPGDCYP3A4
SCHEMBL339310 0.80 TDP1 (0.44) ALDH1A1TDP1HSD17B10HPGDCYP3A4
SCHEMBL29386399 0.79 ALDH1A1 (0.34) ALDH1A1HPGDCYP3A4KDM4EHTT
SCHEMBL25608 0.79 ALDH1A1 (0.34) ALDH1A1HPGDCYP3A4KDM4EHTT
SCHEMBL5972836 0.79 TDP1 (0.34) ALDH1A1TDP1HSD17B10HPGDCYP3A4
SCHEMBL9416205 0.78 CNR2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1631497-A4 LINERLESS LABELS APPLETON PAPER INC (US) 2007-10-17 EP disclosed
US-7125824-B2 Bar codes substrate with two side surface coatings, a thermally-imaging coatings has chromogenic material, 3-[1,1-bis(1,2-dimethylindole-3-yl)ethylene-2-yl]-3-(4-dimethylaminophenyl) -phthalide and Bis(3-Allyl-4-hydroxyphenyl)sulfone developer, the other is pressure sensitive adhesive coatings; nonfading APPLETON PAPERS INC. (US) 2006-10-24 US disclosed
EP-1631497-A2 LINERLESS LABELS Appleton Papers Inc. (US) 2006-03-08 EP disclosed
WO-2004106168-A2 LINERLESS LABELS APPLETON PAPERS INC. (US) 2004-12-09 WO disclosed
US-20040234756-A1 Linerless labels APPLETON PAPERS INC. 2004-11-25 US disclosed