Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864808 | 0.87 | — | — | |
| SCHEMBL10947855 | 0.81 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL10947852 | 0.81 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL15200419 | 0.77 | — | — | |
| SCHEMBL7738840 | 0.77 | CES1 (0.41) | CES2CES1TSHRALDH1A1AKR1B1 | |
| Urea SCHEMBL8671584 | 0.76 | ALDH1A1 (0.40) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL9802273 | 0.75 | — | — | |
| SCHEMBL73010 | 0.75 | — | — | |
| Bicarbonate SCHEMBL4362323 | 0.75 | FFAR3 (0.47) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL15200423 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1795072-B1 | Agents containing carboxylic acid and the use of the same in plant cultivation | BASF SE (DE) | 2016-02-17 | — | — | EP | disclosed |
| EP-1795072-A2 | Agents containing carboxylic acid and the use of the same in plant cultivation | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-13 | — | — | EP | disclosed |
| EP-1531675-B1 | AGENTS CONTAINING CARBOXYLIC ACID AND THE USE OF THE SAME IN PLANT CULTIVATION | BASF AG (DE) | 2007-04-04 | — | — | EP | disclosed |
| EP-1531675-A1 | AGENTS CONTAINING CARBOXYLIC ACID AND THE USE OF THE SAME IN PLANT CULTIVATION | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004023875-A1 | AGENTS CONTAINING CARBOXYLIC ACID AND THE USE OF THE SAME IN PLANT CULTIVATION | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-25 | — | — | WO | disclosed |