Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507197 | 0.82 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL5507260 | 0.81 | PTPN2 (0.34) | PTPN1PTPN2IDO1 | |
| SCHEMBL5998435 | 0.70 | PTPN2 (0.35) | PTPN2 | |
| SCHEMBL4900949 | 0.70 | PTPN1 (0.44) | PTPN1PTPN2 | |
| SCHEMBL16343790 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL14266790 | 0.63 | PTPN1 (0.44) | PTPN1PTPN2 | |
| SCHEMBL5507258 | 0.62 | PTPN1 (0.37) | PTPN1PTPN2 | |
| SCHEMBL13133071 | 0.61 | TSHR (0.46) | — | |
| SCHEMBL5508634 | 0.61 | ALDH1A1 (0.42) | PTPN1PTPN2 | |
| SCHEMBL29728733 | 0.61 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786421-A2 | OXYGEN/NITROGEN HETEROCYCLE INHIBITORS OF TYROSINE PHOSPHATASES | Cengent Therapeutics, Inc. (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006017124-A2 | OXYGEN/NITROGEN HETEROCYCLE INHIBITORS OF TYROSINE PHOSPHATASES | CENGENT THERAPEUTICS, INC. (US) | 2006-02-16 | — | — | WO | claimed |
| EP-1786421-A2 | OXYGEN/NITROGEN HETEROCYCLE INHIBITORS OF TYROSINE PHOSPHATASES | Cengent Therapeutics, Inc. (US) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006017124-A2 | OXYGEN/NITROGEN HETEROCYCLE INHIBITORS OF TYROSINE PHOSPHATASES | CENGENT THERAPEUTICS, INC. (US) | 2006-02-16 | — | — | WO | disclosed |