Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 19/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507265 | 0.85 | ADORA2B (0.67) | ADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL240141 | 0.81 | ADORA2B (1.00) | ADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL1944501 | 0.78 | ADORA2B (1.00) | ADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL4176128 | 0.74 | ADORA2B (0.62) | ADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL3466506 | 0.74 | ADORA2B (0.59) | ADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL3466169 | 0.73 | ADORA2B (0.65) | ADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL1944545 | 0.73 | ADORA2B (0.53) | ADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL5685513 | 0.73 | ADORA2B (0.59) | ADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL5687959 | 0.73 | ADORA2B (0.63) | ADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL1943830 | 0.73 | ADORA2B (0.55) | ADORA2BADORA1ADORA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789053-A2 | METHOD OF WOUND HEALING USING A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2007-05-30 | — | — | EP | claimed |
| WO-2006028810-A2 | METHOD OF WOUND HEALING USING A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2006-03-16 | — | — | WO | claimed |