SCHEMBL5507567

SCHEMBL5507567

[CH2]C(O)(C(=O)C(=C)C)C(=O)C(=C)C

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.40
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2617047 0.71
SCHEMBL21735828 0.71 TDP1 (0.42) TDP1ALDH1A1HSD17B10TSHR
SCHEMBL11224690 0.69
SCHEMBL28849282 0.69 TDP1 (0.31) TDP1
SCHEMBL15822275 0.69 TDP1 (0.35) TDP1ALDH1A1TSHR
SCHEMBL20892753 0.67
SCHEMBL12962523 0.67
Methacrylic Acid SCHEMBL14686495 0.65 ALDH1A1 (0.44) TDP1ALDH1A1HSD17B10TSHR
Methacrylic Acid SCHEMBL6856806 0.65 ALDH1A1 (0.44) TDP1ALDH1A1HSD17B10TSHR
Methacrylic Acid SCHEMBL10488480 0.65 ALDH1A1 (0.44) TDP1ALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111128690-A Method for forming pattern 台湾积体电路制造股份有限公司 2020-05-08 CN disclosed
EP-1789008-A1 REACTIVE FILLER FOR DENTAL CEMENTS DENTSPLY DETREY GmbH (DE) 2007-05-30 EP disclosed
WO-2006013111-A1 REACTIVE FILLER FOR DENTAL CEMENTS DENTSPLY DETREY GMBH (DE) 2006-02-09 WO disclosed