⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL27358024 | 0.76 | — | — | |
| Butane SCHEMBL7375120 | 0.76 | — | — | |
| Butane SCHEMBL11524624 | 0.75 | — | — | |
| Butane SCHEMBL28166696 | 0.74 | — | — | |
| Butane SCHEMBL11513745 | 0.74 | — | — | |
| Butane SCHEMBL19031462 | 0.74 | — | — | |
| Butane SCHEMBL7201206 | 0.74 | TSHR (0.44) | — | |
| Butane SCHEMBL214592 | 0.74 | — | — | |
| Butane SCHEMBL19947538 | 0.74 | — | — | |
| Butane SCHEMBL6577949 | 0.73 | CA1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153034-B1 | GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2007-10-17 | — | — | EP | disclosed |
| US-20050143318-A1 | Growth hormone secretagogues | DODGE JEFFREY A (US) | 2005-06-30 | — | — | US | disclosed |
| US-6828331-B1 | Non-peptidyl in nature and are, therefore, more metabolically stable than growth hormone, growth hormone releasing hormone, or analogs of either of these proteins | ELI LILLY AND COMPANY | 2004-12-07 | — | — | US | disclosed |
| EP-1153034-A1 | GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000049037-A1 | GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 2000-08-24 | — | — | WO | disclosed |