Butane

Butane

SCHEMBL6577949

CCCC.N#CS.N#CS

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.39
NPC1 O15118 1/20 0.32
MTOR P42345 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL5577989 1.00
Butane SCHEMBL16053106 0.96
Propane SCHEMBL6578035 0.86
Propane SCHEMBL19371522 0.86
Propane SCHEMBL11425893 0.86 CA1 (0.60) CA1CA2ALDH1A1TSHR
Hexane SCHEMBL4939829 0.84
Pentane SCHEMBL19371507 0.84 TSHR (0.54) CA1CA2ALDH1A1TSHR
Hexane SCHEMBL19371513 0.84 TSHR (0.50) CA1CA2ALDH1A1TSHR
Propylamine SCHEMBL9666785 0.81
Thiocyanic Acid SCHEMBL6580536 0.81 TSHR (0.57) CA1CA2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113262218-A Application of isothiocyanate compounds 无锡杰西医药股份有限公司 2021-08-17 CN disclosed
CN-113181160-A Application of isothiocyanate compounds 无锡杰西医药股份有限公司 2021-07-30 CN disclosed
EP-3222694-B1 MECHANOCHROMIC LUMINESCENT MATERIAL, MECHANOCHROMIC RESIN OBTAINED BY CROSSLINKING MECHANOCHROMIC LUMINESCENT MATERIAL, METHOD FOR PRODUCING MECHANOCHROMIC LUMINESCENT MATERIAL, AND METHOD FOR PRODUCING MECHANOCHROMIC RESIN JAPAN SCIENCE & TECH AGENCY (JP) 2021-06-09 EP disclosed
CN-105267967-B Combined application of isothiocyanate compounds and anti-cancer drugs acting on or influencing DNA (deoxyribonucleic acid) 无锡杰西医药股份有限公司 2021-05-18 CN disclosed
CN-104117064-B Combined application of isothiocyanate compounds and hormone drugs 无锡杰西医药股份有限公司 2021-02-26 CN disclosed
CN-107109212-B Mechanochromic light-emitting material, mechanochromic resin obtained by crosslinking mechanochromic light-emitting material, and methods for producing both 国立研究开发法人科学技术振兴机构 2020-02-14 CN disclosed
US-10442886-B2 Mechanochromic luminescent material, mechanochromic resin obtained by crosslinking mechanochromic luminescent material, method for producing mechanochromic luminescent material, and method for producing mechanochromic JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2019-10-15 US disclosed
US-20190031820-A1 MECHANOCHROMIC LUMINESCENT MATERIAL, MECHANOCHROMIC RESIN OBTAINED BY CROSSLINKING MECHANOCHROMIC LUMINESCENT MATERIAL, METHOD FOR PRODUCING MECHANOCHROMIC LUMINESCENT MATERIAL, AND METHOD FOR PRODUCING MECHANOCHROMIC JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2019-01-31 US disclosed
EP-3222694-A1 MECHANOCHROMIC LUMINESCENT MATERIAL, MECHANOCHROMIC RESIN OBTAINED BY CROSSLINKING MECHANOCHROMIC LUMINESCENT MATERIAL, METHOD FOR PRODUCING MECHANOCHROMIC LUMINESCENT MATERIAL, AND METHOD FOR PRODUCING MECHANOCHROMIC RESIN Japan Science and Technology Agency (JP) 2017-09-27 EP disclosed
EP-1120435-B1 APPARATUS AND METHOD FOR PRODUCING RESIN TEIJIN LTD (JP) 2004-05-06 EP disclosed
US-6562936-B1 Resin excellent in hydrolysis and heat stability such as a reduction in molecular weight at the time of molding and color retention and moldability such as releasability and transferability, rarely experiences residence deterioration TEIJIN LIMITED (JP) 2003-05-13 US disclosed
US-6509435-B1 Heat resistance, stability; moldings TEIJIN LIMITED (JP) 2003-01-21 US disclosed
EP-1191049-A1 POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2002-03-27 EP disclosed
EP-1120435-A1 APPARATUS AND METHOD FOR PRODUCING RESIN TEIJIN LIMITED (JP) 2001-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10442886-B2 Mechanochromic luminescent material, mechanochromic resin obtained by crosslinking mechanochromic luminescent material, method for producing mechanochromic luminescent material, and method for producing mechanochromic RAD51, PIEZO1, F12 CA1 2764/4885CA2 1756/4885ALDH1A1 2469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.