Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.67 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | THPO | P40225 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5992981 | 1.00 | ADORA2A (0.67) | ADORA2ATSHRADORA2BADORA3PMP22 | |
| SCHEMBL5507638 | 1.00 | ADORA2A (0.67) | ADORA2ATSHRADORA2BADORA3PMP22 | |
| SCHEMBL5504529 | 0.98 | ADORA2A (0.70) | ADORA2ATSHRADORA2BADORA3PMP22 | |
| SCHEMBL5510434 | 0.97 | ADORA2A (0.70) | ADORA2ATSHRADORA2BADORA3PMP22 | |
| SCHEMBL6266706 | 0.96 | AHCY (0.65) | ADORA2ATSHRADORA2BADORA3PMP22 | |
| SCHEMBL6259026 | 0.96 | AHCY (0.65) | ADORA2ATSHRADORA2BADORA3PMP22 | |
| SCHEMBL6257699 | 0.93 | AHCY (0.62) | ADORA2ATSHRADORA2BADORA3PMP22 | |
| SCHEMBL6256707 | 0.93 | AHCY (0.62) | ADORA2ATSHRADORA2BADORA3PMP22 | |
| SCHEMBL6257614 | 0.92 | ADORA2A (0.69) | ADORA2ATSHRADORA2BADORA3PMP22 | |
| SCHEMBL5506309 | 0.90 | ADORA1 (0.64) | ADORA2ATSHRADORA2BADORA3PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537133-B1 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | CV THERAPEUTICS INC (US) | 2007-07-25 | — | — | EP | disclosed |