Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.36 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.36 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.36 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 5/20 | 0.34 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5504623 | 0.99 | TLR8 (0.40) | TLR8CSNK1A1CSNK1DPRKCDPAK1 | |
| SCHEMBL5276268 | 0.97 | TLR8 (0.42) | TLR8CSNK1A1CSNK1DPRKCDPAK1 | |
| SCHEMBL18587589 | 0.88 | TLR8 (0.48) | TLR8CSNK1A1CSNK1DPRKCDPAK1 | |
| SCHEMBL5271662 | 0.87 | TLR8 (0.43) | TLR8CSNK1A1CSNK1DPRKCDPAK1 | |
| SCHEMBL18587553 | 0.87 | TLR8 (0.50) | TLR8CSNK1A1CSNK1DPRKCDPAK1 | |
| SCHEMBL18587595 | 0.86 | TLR8 (0.46) | TLR8CSNK1A1CSNK1DPRKCDPAK1 | |
| SCHEMBL18588106 | 0.84 | TLR8 (0.42) | TLR8CSNK1A1CSNK1DPRKCDPAK1 | |
| SCHEMBL18585619 | 0.83 | TLR8 (0.52) | TLR8TLR7 | |
| SCHEMBL18587114 | 0.83 | TLR8 (0.46) | TLR8CSNK1A1CSNK1DPRKCDPAK1 | |
| SCHEMBL5075205 | 0.79 | TLR8 (0.43) | TLR8CSNK1A1CSNK1DPRKCDPAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1850849-A2 | METHOD OF PREFERENTIALLY INDUCING THE BIOSYNTHESIS OF INTERFERON | Coley Pharmaceutical Group, Inc. (US) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006091647-A2 | METHOD OF PREFERENTIALLY INDUCING THE BIOSYNTHESIS OF INTERFERON | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-31 | — | — | WO | disclosed |