Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11106067 | 1.00 | SLC7A5 (0.41) | SLC7A5SLC1A2SLC1A3SLC1A1NOS1 | |
| SCHEMBL7132175 | 0.94 | SLC7A5 (0.39) | SLC7A5SLC1A2SLC1A3SLC1A1NOS1 | |
| SCHEMBL29274071 | 0.92 | SLC1A2 (0.39) | SLC7A5SLC1A2SLC1A3SLC1A1NOS1 | |
| SCHEMBL28025146 | 0.85 | NOS1 (0.40) | SLC7A5SLC1A2SLC1A3SLC1A1NOS1 | |
| SCHEMBL3204138 | 0.84 | SLC7A5 (0.42) | SLC7A5SLC1A2SLC1A3SLC1A1NOS1 | |
| SCHEMBL7814662 | 0.83 | NOS1 (0.37) | SLC7A5NOS1NOS3NOS2ALDH1A1 | |
| SCHEMBL31733944 | 0.83 | NOS1 (0.37) | SLC7A5NOS1NOS3NOS2ALDH1A1 | |
| SCHEMBL27656864 | 0.83 | KMT2A (0.39) | SLC7A5SLC1A2SLC1A3SLC1A1NOS1 | |
| SCHEMBL4106257 | 0.83 | KMT2A (0.39) | SLC7A5SLC1A2SLC1A3SLC1A1NOS1 | |
| SCHEMBL1066621 | 0.83 | KMT2A (0.39) | SLC7A5SLC1A2SLC1A3SLC1A1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831241-A2 | METHOD FOR SOLID-PHASE PEPTIDE SYNTHESIS AND PURIFICATION | AplaGen GmbH (DE) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006056443-A2 | METHOD FOR SOLID-PHASE PEPTIDE SYNTHESIS AND PURIFICATION | APLAGEN GMBH (DE) | 2006-06-01 | — | — | WO | disclosed |