SCHEMBL5508258

SCHEMBL5508258

CCCC(Nc1ccccc1)(C(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.50
CYP2C19 P33261 2/20 0.50
ALOX12 P18054 1/20 0.50
MAPT P10636 4/20 0.44
ALOX5 P09917 1/20 0.43
ALDH1A1 P00352 6/20 0.41
HPGD P15428 1/20 0.41
RECQL P46063 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
NAPRT Q6XQN6 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HTT P42858 2/20 0.39
LMNA P02545 1/20 0.39
EPHX1 P07099 3/20 0.39
KDM4E B2RXH2 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5513747 0.88 GAA (0.54) GAACYP2C19ALOX12MAPTALOX5
SCHEMBL5523823 0.85 MAPT (0.42) GAACYP2C19ALOX12MAPTALOX5
SCHEMBL27512193 0.77 SRC (0.41) GAAMAPTALOX5ALDH1A1HPGD
SCHEMBL5524157 0.77 SMN1; SMN2 (0.47) GAAALOX12ALDH1A1HSD17B10HTT
SCHEMBL10765101 0.75 GAA (0.48) GAACYP2C19ALOX12MAPTALOX5
SCHEMBL5509354 0.75 NPC1 (0.42) GAACYP2C19ALOX12HTTLMNA
SCHEMBL10980611 0.75 MAPT (0.52) GAAMAPTALDH1A1HPGDRECQL
SCHEMBL29142864 0.74 MAPT (0.44) GAACYP2C19ALOX12MAPTALOX5
SCHEMBL7768186 0.74 GAA (0.50) GAACYP2C19ALOX12MAPTALOX5
SCHEMBL22501165 0.73 MAPT (0.42) GAACYP2C19ALOX12MAPTALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed