SCHEMBL5513747

SCHEMBL5513747

CCCCCC(Nc1ccccc1)(C(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.54
EPHX1 P07099 3/20 0.46
ALDH1A1 P00352 2/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.44
ALOX12 P18054 1/20 0.43
CYP2C19 P33261 1/20 0.43
ICMT O60725 1/20 0.42
ALB P02768 1/20 0.42
SOAT2 O75908 1/20 0.42
SOAT1 P35610 1/20 0.42
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
NAAA Q02083 1/20 0.41
TRPV1 Q8NER1 1/20 0.41
MAPT P10636 1/20 0.41
HSD17B10 Q99714 1/20 0.40
EGFR P00533 1/20 0.40
ALOX5 P09917 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5508258 0.88 GAA (0.50) GAAEPHX1ALDH1A1HTTNPSR1
SCHEMBL5523823 0.80 MAPT (0.42) GAAEPHX1ALDH1A1ALOX12CYP2C19
SCHEMBL10765101 0.78 GAA (0.48) GAAEPHX1ALDH1A1HTTNPSR1
SCHEMBL28841582 0.77 GAA (0.48) GAAEPHX1ALDH1A1HTTNPSR1
SCHEMBL7768186 0.77 GAA (0.50) GAAEPHX1ALDH1A1HTTNPSR1
SCHEMBL1454677 0.75 GAA (0.47) GAAEPHX1ALDH1A1HTTNPSR1
SCHEMBL11329795 0.75 GAA (0.47) GAAEPHX1ALDH1A1HTTNPSR1
SCHEMBL23633882 0.74 GAA (0.46) GAAEPHX1ALDH1A1HTTNPSR1
SCHEMBL9146997 0.74 GAA (0.46) GAAEPHX1ALDH1A1HTTNPSR1
SCHEMBL1454049 0.74 GAA (0.46) GAAEPHX1ALDH1A1HTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed