Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525032 | 0.98 | FAAH (0.44) | FAAHTRPV1SMN1; SMN2F10QPCT | |
| SCHEMBL5512361 | 0.91 | F10 (0.43) | FAAHTRPV1F10 | |
| SCHEMBL5506911 | 0.91 | FAAH (0.40) | FAAHTRPV1F10LMNA | |
| SCHEMBL5505663 | 0.89 | F10 (0.43) | FAAHTRPV1F10 | |
| SCHEMBL5509410 | 0.89 | F10 (0.47) | FAAHTRPV1SMN1; SMN2F10MEN1 | |
| SCHEMBL5502514 | 0.89 | FAAH (0.39) | FAAHTRPV1F10KMT2AHTT | |
| SCHEMBL5512752 | 0.89 | FAAH (0.38) | FAAHTRPV1F10LMNA | |
| SCHEMBL4461044 | 0.88 | F10 (0.46) | FAAHSMN1; SMN2F10MEN1KMT2A | |
| SCHEMBL5506699 | 0.88 | F10 (0.38) | FAAHTRPV1F10KMT2AHTT | |
| SCHEMBL5506981 | 0.88 | F10 (0.47) | FAAHTRPV1SMN1; SMN2F10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |